N6-methyladenosine Modification Regulates Iron Death Through Hepatic Stellate Cell Autophagy Signaling Pathway
Iron death is a recently discovered non-apoptotic form of cell death, which is characterized by iron-dependent lipid peroxidation. However, the exact underlying mechanism is still poorly understood. ...
Scientists Utilizes 3D Printing Technology to Create A Complete Model of Glioblastoma
At present, the commonly used model for tumor research is tumor cells grown in 2D culture dishes, but this model lacks the interaction between tumor and stroma, and cannot well simulate the complex ...
Double-arm Molecules Targeting CLTA-4 and CD47 may Specifically eliminate Treg Cells in Tumors and Effectively Promote Anti-tumor Immune Responses
In a new study, researchers from the University of Texas Southwestern Medical Center, Aetio Biotherapy and the Institute of Biophysics of the Chinese Academy of Sciences found that a double-arm ...
Sars-cov-2 Specific Immune Response in Patients Recovering from COVID-19
By collecting the blood of convalescent patients with COVID-19, the sars-cov -2 specific humoral immunity and cellular immunity of these discharged patients were studied. In the fourth 11 months ...
Structural Damage to The Substantia Nigra of The Midbrain Dffects Sequential Working Memory in Parkinson's Patients
The Journal of Neuroscience published an online research paper entitled "The structural integrity of the substantia nigra in Parkinson's disease is related to sequential working memory". Combining ...
Nature Magazine First Proposed Cancer Environmental Immunotherapy with Broad Application Prospects
Although immune-based cancer treatments have achieved remarkable success, not everyone responds to these methods, and cancer recurrence can occur. Scientists all over the world are racing to find ...
Revolution Breakthrough: AI May Accurately Predict Protein Structure Based on Amino Acid Sequence
The artificial intelligence (AI) network developed by Google AI makes DeepMind stand out and has made a huge leap in solving one of the toughest challenges in biology-determining the 3D shape of a ...
Potential Immunotherapy Targets Discovered by CRISPR That Reveals The Immune Escape of Cancer Cells
Cancer immunotherapy is a revolutionary breakthrough that changes the landscape of cancer treatment. However, even though there are already many FDA-approved immunotherapies on the market, only a ...
New Study Proves That Artificial Intelligence may Detect Cancer Mutations
Researchers from the European Institute of Bioinformatics, the Wellcome Sanger Institute and other institutions and their collaborators have developed an artificial intelligence algorithm that ...
Ways to Solve The Blood-brain Barrier Injury of Alzheimer's Disease Published by Nat Med
By developing a laboratory-designed model of the human blood-brain barrier (BBB), neuroscientists at the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology ...