Triggering Cuprotosis to Fight Leukemia
It is well known that multicellular organisms undergo various predetermined and precisely controlled programmed cell death during development, such as apoptosis, necroptosis, pyroptosis, and ...
Science's Tiny Drug Delivery Robots
When you take a pill, only a minimal amount of the drug ultimately reaches the diseased site, while the majority distributes throughout the body. This systemic administration often leads to ...
In Vivo CAR-T: The Game Changer
Over the past three decades, immunotherapy has undergone significant transformation, driven by advancements in monoclonal antibodies, antibody-drug conjugates, cytokines, immune cell connectors, DNA ...
Brain SOS: The Hidden Start of Hypertension
Did you know that over 1 billion people worldwide suffer from hypertension? Even more alarming is that people with hypertension have a 1.2 to 1.5 times higher risk of developing cognitive impairment ...
An Old Drug's New Mission: Deflate Cancer Risk
Breast cancer is one of the most common and deadliest cancers among women worldwide. Statistics show that over 2 million women are diagnosed with breast cancer each year, with about one-tenth ...
Unlocking Fertility: How Sperm 'Rev Up' Energy for Success!
Approximately one in six couples worldwide face infertility, with male factors accounting for about half of these. Meanwhile, approximately 50% of pregnancies worldwide are unintended each year. ...
DNA Traffic Jams: Meet KCTD10, the Guardian of Genome Safety!
In every cell of your body, a sophisticated molecular traffic flow takes place: the replication machinery (replisome), like a high-speed sports car, rapidly copies DNA to ensure genetic information ...
How Synaptic Priming Could Transform Antidepressant Therapy?
Ketamine and dexketamine rapidly relieve depression, with effects occurring within hours of a single dose and their effects often persisting for days to weeks after drug elimination. They are not ...
How Microglia and Astrocytes Shape Synapse Remodeling
In a new study, a research team led by Dr. Dorothy P. Schafer and Dr. Travis E. Faust of the University of Massachusetts Chan School of Medicine explains how two distinct cell types in the ...
Astrocytes: The Secret Boosters of Long-Term Memory Stability!
Memory is a highly unstable part of our brains. Certain experiences that are crucial for survival, carry strong emotional weight, and are frequently repeated can form lasting memories through unique ...