KO vs. Cre vs. Flox: A Guide to the Gene-Editing Menagerie
In the fields of biology and medical research, breakthroughs in gene editing technology have provided strong support for gene function analysis, and gene-edited mice, as a core research tool, have ...
5 Steps to Better HE Staining
HE staining is the most fundamental and core technique in pathological diagnosis and basic research. High-quality slides require clear contrast between cell nuclei and cytoplasm, a clean background ...
A Comprehensive Guide to Eight Organoid Culture Systems
Organoid technology has firmly established itself as a cornerstone of modern life science. However, the successful generation of these intricate, self-organized 3D structures extends far beyond basic ...
A Comparative Look at DC, CIK, NK, and TIL Therapies
Cancer immunotherapy is an emerging method that utilizes the patient's own immune system to attack cancer cells. Immune cells are extracted and expanded, then reinjected into the patient's body ...
From 2D to 3D: A Century-Long Evolution of In Vitro Tumor Models
In the protracted battle against cancer, one of the frontiers of human ingenuity is the construction of in vitro models in the laboratory that mimic real tumors. This is more than just simple cell ...
CAR-T Has Emerged as A New Force in Autoimmune Diseases. What Challenges Will It Face?
CAR-T cell therapy has achieved remarkable results in the field of hematological malignancies and is expanding to clinical trials for solid tumors, infectious diseases, and autoimmune diseases. In ...
Overview of Organoid Research
Organoids are a complex collection of cells grown in a three-dimensional (3D) medium, which are derived from embryonic stem cells (ESC), induced pluripotent stem cells (iPSC), or adult stem cells ...
M-FISH and Clonality Analysis: Advancing Genetic Research and Understanding Cancer
In recent years, researchers have been making significant strides in the field of genetics, aiming to unravel the complexities of various diseases, including cancer. One important technique that has ...
Immunology for The Immune System: Contributing to The Development of Many Common Disorders
The immune system protects against infection through various lines of defense. When the immune system does not function properly, it can lead to diseases such as autoimmunity, allergies and cancer. ...
Thoughts on The Differences Between Gene Therapy and Immunotherapy
As cancer medicine advances, more and more new therapies are being used to treat cancer. Gene therapy and immunotherapy are among the best. In fact, the two popular new treatments, immunotherapy and ...